JAK Inhibition in STAT1 Gain-of-Function-Mediated Treatment-Resistant Autoimmune Hepatitis

N Engl J Med. 2024 Jan 18;390(3):284-286. doi: 10.1056/NEJMc2311867.
No abstract available

Publication types

  • Letter

MeSH terms

  • Gain of Function Mutation
  • Hepatitis, Autoimmune* / drug therapy
  • Hepatitis, Autoimmune* / genetics
  • Humans
  • Janus Kinases* / antagonists & inhibitors
  • Janus Kinases* / metabolism
  • STAT1 Transcription Factor* / genetics

Substances

  • Janus Kinases
  • STAT1 protein, human
  • STAT1 Transcription Factor